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  1. USA Small Ship River Cruises | Intimate U.S. Coastal Cruises

    American Cruise Lines offers 50+ US River Cruises along the Mississippi, Columbia & Snake Rivers, New England & Alaska Waterways on luxurious Small Cruise Ships

  2. Mississippi River Cruises | Best Way to Cruise the Mississippi

    For the ultimate river voyage, American Cruise Lines presents the 16-day Grand Heartland cruise or the 23-day Complete Mississippi River cruise, both traveling between New Orleans, LA and …

  3. Columbia & Snake River Cruises - American Cruise Lines

    Trace the route of Lewis and Clark aboard modern riverboats. Cruise dramatic gorges, waterfalls, Mount St. Helens, plus sample Pacific Northwest cuisine.

  4. Southeast U.S. & Intracoastal Waterway Cruises - American Cruise …

    Cruise Southeastern rivers and coastlines exploring historic coastal towns, lush waterways, charming ports, all-inclusive service, and regional cuisine.

  5. Charming New England Cruises - American Cruise Lines

    From cultural landmarks to scenic landscapes, each destination along the Maine Coast cruise offers a unique blend of history, natural beauty, and local flavor, with stops in Portland, Bath, …

  6. River Cruises | Explore U.S. Rivers with American Cruise Lines

    Cruise America’s great rivers aboard a modern small ship with American Cruise Lines. Explore the Mississippi, Ohio, Hudson, and more on scenic, history-rich voyages.

  7. Find a Cruise | Search 50+ Small Ship Cruise Itineraries in the U.S.

    Search over 50 U.S. cruise itineraries by region, date, or ship class. View highlights, local excursions, rates, and availability to find your perfect cruise.

  8. Columbia River Gorge Cruise | River Cruises in Portland, Oregon

    Follow the path of Lewis & Clark on a seven day Columbia River Gorge cruise with waterfalls, towering cliffs, and onboard experts who bring history to life.

  9. About American Cruise Lines | U.S. River & Small Ship Cruises

    Learn about American Cruise Lines, an all-American cruise company offering small ship and river cruises across 35 states and 50+ itineraries.

  10. American Cruise Lines Sails into 2025: 21 Small Ships & Riverboats ...

    Next year, the world’s only 100% U.S.-flagged fleet of riverboats and small cruise ships, will sail over 50 different itineraries, including brand new cruises on the Mississippi River, the …