The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Precision oncology led to the establishment ...

Cancer remains a leading cause of death globally, with lung cancer being particularly lethal. Despite advancements in diagnostics and therapies, the five-year survival rates for advanced tumors have ...

In mice, Notch1 is expressed uniformly throughout the endocardium during the initial stages of heart valve formation. How, then, is Notch activated specifically in the valve forming regions? To answer ...

The following is a summary of “A genome-wide association meta-analysis links hidradenitis suppurativa to common and rare sequence variants causing disruption of the Notch and Wnt/β-catenin signaling ...

I’m still chugging along on an iPhone 12 Pro, which means I don’t get much hands-on time with the Dynamic Island on a day-to-day basis. Or at least I didn’t, that is, until I discovered a little app ...

A phase 1 clinical trial of DB-020 intratympanic injections administered prior to high-dose cisplatin chemotherapy to reduce ototoxicity. This is an ASCO Meeting Abstract from the 2024 ASCO Annual ...

Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, Assam, India Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781039 ...