NFL Week 16 picks, predictions for every NFL game this week, including Rams-Seahawks, Patriots-Ravens, Chargers-Cowboys, Chiefs-Titans, Packers-Bears.

In Week 15, there were four games with double-digit spreads, and 44-year-old Philip Rivers helped lead his team to the only cover among those underdogs. He's already a betting spread legend.

Colts quarterback Philip Rivers should face less pressure his second week back in the NFL, as his team plays the 49ers on "Monday Night Football."

Bills (10-4, -10 1/2) over @Browns (3-11), 28-16: Buffalo, buoyed by huge rally triumph in New England, can clinch playoffs with win here if Texans and Colts also lose. More important, Bills still chase AFC East title and won’t let lowly Browns get in way. Josh Allen keeps showing he can beat anything ... including his own middling defense.

Microsoft Copilot picks all of the NFL Week 17 games after going 12-4 predicting the results of the previous week's contests.

Seattle will likely be too tough for the 49ers, and Caleb Williams and the Bears can't expect the Rams to fold like the Packers did.

In a turnover-filled game that matched the sloppy, snowy-weather forecast, the New England Patriots leaned on their defense and some timely big plays on offense to record a 28-16 victory over the Houston Texans in an AFC divisional round playoff game Sunday.

New England intercepted C.J. Stroud four times to advance to the club's first conference title game since the 2018 postseason.