The first automated, web-based application that enables routine use of enzymatic digestions to improve N-glycan structural analyses, GlycanAnalyzer, has been released from New England Biolabs (NEB).

At the heart of Toti-N-Seq lies an engineered protein, Stv-Fg, derived from modifying the natural glycan-binding protein Fbs1. This fusion protein binds non-selectively to all N-glycan types, enabling ...

A type of glycan called “N-glycan” is usually extended by the actions of several enzymes (glycosyltransferases). The terminal sugar “sialic acid” increases protein stability in blood. Once B4GALNT3 ...

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the ...

Bacterial infections are frequently based on the binding of lectinlike adhesins to specific glycan determinants exposed on host cell receptors. These interactions confer species-specific recognition ...

Gifu University scientists have uncovered how a brain-specific enzyme reshapes protein-linked sugar chains to facilitate the ...

Glycomics is defined as the study of both free sugars and of the complex sugar chains (glycans) that reside in glycoconjugates such as glycoproteins and glycolipids. Given the effects of ...

Microscopic droplets fluoresce bright blue with specks of green. Five droplets in this image (two at the top, two near the center, and one near the bottom) fluoresce blue in varying brightness; each ...

Sepsis—an extreme inflammatory response in the bloodstream caused by a serious infection—could be responsible for as many as 11 million deaths worldwide per year, according to a 2020 report from the ...