Granzyme proteases are a family of serine enzymes principally secreted by cytotoxic T cells and natural killer cells to induce cell death in virally infected or malignant targets. Traditionally ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...

New research represents a notable step forward in designing enzymes from scratch. With their approach, the authors designed an enzyme that uses a covalent intermediate to catalyze a two-step reaction, ...

In just two neutron experiments, scientists have uncovered amazing information about the role of an enzyme that could assist ...