A new report examined optic nerve lesion length, measured on brain magnetic resonance imaging, at the acute phase of ON in 51 individuals. Optic nerve lesion length was significantly associated with ...

Multiple Sclerosis Cladribine tablets have a rapid onset of improvements in MRI outcomes within the first year in patients with a first demyelinating event at high risk of converting to clinically ...

Acute demyelinating optic neuritis (referred to herein as optic neuritis) is one of the most common manifestations of MS and often occurs as a first demyelinating event. Patients present with loss of ...

Aimee Pasqua Borazanci; Meghan K. Harris; Robert N. Schwendimann; Eduardo Gonzalez-Toledo; Amir H. Maghzi; Masoud Etemadifar; Nadejda Alekseeva; James Pinkston; Roger E. Kelley; Alireza Minagar Owing ...

Animal models of central nervous system (CNS) demyelination, including toxin-induced focal demyelination and immune-mediated demyelination through experimental autoimmune encephalomyelitis (EAE), have ...

An antibody appears to make a big difference between multiple sclerosis and other disorders affecting the protective myelin sheath around nerve fibers, report Tohoku University scientists and ...

A 62 year-old woman with multiple sclerosis was admitted to the hospital for confusion. She had moderate cognitive dysfunction. All four limbs were spastic and weak, and she was incontinent of urine.

We present the case of a 37‑year‑old woman with severe, drug‑resistant rheumatoid arthritis. The patient has been previously treated with several disease‑modifying anti‑rheumatic drugs as well as ...

What caused a previously healthy, 55-year-old woman to develop neurological symptoms including right-sided headache, confusion, blurry vision, and numbness and weakness affecting her right arm and leg ...

A 43 year-old man had a twenty year history of MS, presenting initially with optic neuritis. Over the past ten years, he developed progressive weakness, numbness and ataxia in the lower extremities.