A research team has identified the transcription factor C/EBPγ as a novel regulator that simultaneously promotes ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Single-stranded DNA-binding proteins (SSBs) are central guardians of genome integrity, selectively coating exposed single-stranded DNA (ssDNA) intermediates that arise during replication, ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to separate ...

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms.

For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms.

Scientists have captured the most detailed structural images to date of a specific type of protein's DNA repair process, a finding that could reveal ways to inhibit the effects of BRCA1 and BRCA2 ...