Journavx (suzetrigine) can cause side effects ranging from mild to serious. More common side effects include muscle spasms and itchiness. If side effects from Journavx become difficult to tolerate, ...

Age-dependent differences in pharmacokinetics exist for metabolically cleared medications. Differential contributions in the cytochrome P450 3A (CYP3A), CYP2C, and flavin-containing monooxygenases ...

Ibrutinib's metabolism by CYP3A makes it susceptible to drug interactions, affecting its serum concentration significantly with CYP3A modulators. Despite frequent drug interactions, overall survival ...

Application of pharmacokinetic (PK)-guided 5-fluorouracil (FU) in clinical practice. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This abstract does not include a full text ...