Watch the top touchdowns from Week 16 of the 2025 NFL season. Highlights from the Week 16 matchup between the San Francisco 49ers and the Indianapolis Colts during the 2025 NFL season.

The SportsLine Machine Learning Model has locked in its top Week 16 NFL anytime TD picks for players like Amon-Ra St. Brown, Bucky Irving and Omarion Hampton

Power ranking the NFL’s top 10 quarterbacks heading into Week 17, evaluating recent form, season-long production, and who’s playing the best football right now.

Sunday Night Football in Week 16 features a ton of talented offensive players, as the New England Patriots hit the road to play Lamar Jackson and the Baltimore

After a run of 10 straight postseasons, the Chiefs won't be playing for a Super Bowl berth. Backup Gardner Minshew will now lead the offense in Week 16 as Kansas City visits the Tennessee Titans, who are in contention for the top pick in next year's NFL Draft.

The Falcons also elevated edge rusher Khalid Kareem and wide receiver Chris Blair from the practice squad for Week 16. Kareem has appeared in 30 games over the last five seasons, recording 34 tackles (17 solo),