Membranes define the boundaries of cells and their major organelles, enabling cellular compartmentalization that is essential for cell function. Membranes are also signalling platforms that mediate ...

Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their ...

Share on Pinterest Our lipid profile may hold vital clues about our health. Image credit: Yamada Taro/Getty Images. Lipids are fatty compounds that are one of the building blocks needed to make living ...

Disrupted lipid metabolism in the central nervous system triggers α-Syn aggregation, ferroptosis, mitochondrial dysfunction, and neuroinflammation. All of these contribute to the onset and progression ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

ESC Huge Decreases in LDL Cholesterol With Alirocumab: ODYSSEY Tested in high-risk CVD patients, heterozygous-FH patients, and patients intolerant to statins, treatment with alirocumab resulted in as ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

This review paper summarizes numerous research studies that address the role of kidney cholesterol and lipid accumulation in the development and progression of chronic kidney disease (CKD). ZyVersa’s ...